Medication Information:
Ondansetron (generic) ~ Zofran (brand) Classification: Selective serotonin receptor antagonist; antiemetic
Common Usage: Ondansetron is most commonly used to treat postoperative
nausea and vomiting and the nausea and vomiting associated with chemotherapy and
radiotherapy. It has also been used for treatment of bulimia nervosa. CommonDosages: The dosage varies greatly depending on the type of therapy.
See drug labeling for details. CommonMajor Side Effects: Constipation is the most common side effect reported
among patients receiving ondansetron to relieve the nausea and vomiting
associated with chemotherapy. Other side effects include headache,
dizziness, rash, and blurred vision. This is not a complete list of all
known or potential adverse effects. Interactions with Other Medications: Ondansetron does not appear to
induce or inhibit the cytochrome P-450 drug-metabolizing enzyme system.
Drugs that induce or inhibit cytochrome P-450 enzymes may alter the clearance of
ondansetron. This is not a complete list of all known or potential drug
interactions. Identification: Ondansetron is available as Zofran in 4- and 8-mg
tablets. The 4-mg tablets are white, oval, film coated and engraved with
"Zofran" on one side and "4" on the other. The 8-mg tablets are yellow,
oval, film coated and engraved with "Zofran" on one side and "8" on the other. Zofran is also available
as a 2-mg/mL injectable solution, a 4-mg/mL oral solution and a 32-mg/mL
intravenous solution. Storage: Store this medication at normal room temperature (59° F to 86°
F) in a tightly closed, light- and moisture-resistant container. If you
have difficulty opening child-resistant containers, your pharmacist can provide
a container that is easier to open. Keep the medication out of direct
sunlight and avoid storing it in a warm or humid area - such as the bathroom or
kitchen - to prevent deterioration. To prevent accidental poisoning, keep
all medications out of the reach of children. Do not take an expired
medication. Do not transfer medication from one container to another.
Carefully discard discontinued medication where children cannot find it. Edited byLawrence H. Price, M.D. ASERVICE OF…. Psychopharmacology Update
Note: These guidelines are for general information only.For more specific information, consult your physician orpharmacist. | 
