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Medication Information:

***UPDATED***
Aripiprazole (generic) ~ Abilify (brand)

Classification: Antipsychotic.
Common Usage:
Aripiprazole is indicated for the treatment of schizophrenia in adults. The safety and efficacy of aripiprazole has not been established in pediatric patients (younger than 18).

Common Doses:  The recommended starting dose of aripiprazole in adults is 10 or 15 mg/day taken once daily.  Dosage increases should not be made earlier than two weeks after starting aripiprazole.  Doses above 15 mg mg/day have not been shown to be more effective than doses of 10 or 15 mg/day.

Important Side Effects: The most common side effects associated with aripiprazole include headache, weakness, fever, nausea, vomiting, constipation, anxiety, insomnia, lightheadedness, somnolence, a sense of restlessness, tremor, rhinitis, coughing, coughing, rash and blurred vision.

Aripiprazole and other antipsychotic medications have been associated in rare cases with neuroleptic malignant syndrome (NMS), a potentially fatal, but treatable condition.  Symptoms of NMS include excessive activity, muscle rigidity, altered mental status and fever.

A syndrome of abnormal involuntary movements of the mouth, tongue, and extremities which are potentially irreversible, called tardive dyskinesia (TD), has also developed in some patients taking antipsychotic medications, usually later in treatment.

If you are planning to become pregnant, are pregnant or are a nursing mother, the potential benefits of this drug must be weighed against the possible hazards.  Discuss the issues in advance with all of your health care providers.

This is not a complete list of all known or potential adverse effects.  Notify your prescriber or pharmacist of any symptoms that have started since you began taking this medication, changing its dose, or adding or changing other medication or diet.  Take care when performing any tasks (for example, driving or operating machinery) that requires your attention until you have experience with this drug and are confident you can perform the task safely.

Interactions with Other Medications: Ketoconazole (Nizoral) may increase the levels of aripiprazole in the blood stream, and the dose of aripiprazole should be decreased when the two medications are taken together.  Quinidine (Quinidex) may increase the levels of aripiprazole in the blood stream, and the dose of aripiprazole should be decreased when the two medications are taken together.  Carbamazepine (Epital) may decrease the levels of aripiprazole in the blood stream, and the dose of aripiprazole should be reduced when carbamazepine is discontinued.

This is not a complete list of all known or potential drug interactions.  To help prevent problems, always make sure that your pharmacist and all prescribers know about all medications you are taking, including over-the-counter drugs; dietary herbal supplements; folk or home remedies; or unusual foods, drinks, or dietary habits.

CommonDosages: The recommended starting dose of aripiprazole is 10 or 15 mg/day taken once daily.  Dosage increases should not be made earlier than two weeks after starting aripiprazole.  Doses above 15 mg/day have not been shown to be more effective than doses of 10 or 15 mg/day.

Identification: Aripiprazole is available as Abilify in 10-, 15-, 20- and 30-mg tablets.  The 10-mg tablets are pink, modified rectangular and debossed with "A-008" on one side and "10" on the other.  The 15-mg tablets are yellow, round and debossed with "A-009" on one side and "15" on the other.  The 20-mg tablets are white, round and debossed with "A-010" on one side and "20" on the other.  The 30-mg tablets are pink, round and debossed with "A-011" on one side and "30" on the other.

Storage: Store this medication at normal room temperature (59° F to 86° F) in a tightly closed, light- and moisture-resistant container.  If you have difficulty opening child-resistant containers, your pharmacist can provide a container that is easier to open.  Keep the medication out of direct sunlight and avoid storing it in a warm or humid area - such as the bathroom or kitchen - to prevent deterioration.  To prevent accidental poisoning, keep all medications out of the reach of children.  Do not take an expired medication.  Do not transfer medication from one container to another.  Carefully discard discontinued medication where children cannot find it.

Edited by Henrietta L. Leonard M.D.

ASERVICE OF…. Psychopharmacology Update
Note: These guidelines are for general information only.For more specific information, consult your physician orpharmacist.

 

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