Medication Information:
Amphetamine mixed salts, extended release amphetamine mixed salts (Generic) - Adderall, Adderall XR (Brand)

Classification: Psychostimulant
Common Usage: Adderall is indicated for the treatment of attention-deficit/hyperactivity disorder (ADHD) in adults and in children ages three and older it is also indicated for narcolepsy.

Extended-release Adderall (XR) is indicated for treatment of ADHD only in adults and in children ages six and older.

For ADHD, these medications should be prescribed as part of a multimodal treatment plan with close physician supervision.

Major Side Effects: The most common side effects in patients using these medications are anorexia (loss of appetite) and insomnia. Other possible side effects include nausea, dizziness, heart palpitations, headache, changes in blood pressure or pulse and rash. Administration of Adderall or Adderall XR may exacerbate symptoms of behavior disturbances and though disorder in psychotic patients. As with other psychostimulants indicated for ADHD, there is a potential for precipitating motor or vocal tics in Tourette's disorder.

These medications should be taken with caution in people who have a history of drug dependence or alcoholism. Abuse of Adderall or Adderall XR may lead to tolerance and dependence. If the drug is withdrawn suddenly after prolonged high-dosage administration, extreme fatigue or depression may occur.

This is not a complete list of all known or potential adverse effects.  Notify your prescriber or pharmacist of any symptoms that have started since you began taking this medication, changing its dose, or adding or changing other medication or diet.  Take care when performing any task (for example, driving or operating machinery) that requires your attention until you have experience with this drug and are confident you can perform the task safely.

Interactions with Other Medications: Acidifying agents such as ascorbic acid (Vitamin C) and fruit juices may lower the absorption of these medications. Conversely, agents that are alkalinizing such as sodium bicarbonate (Alka Seltzer) increase absorption.

Caution should be used when ziprasidone is taken in combination with other drugs affecting the central nervous system. Also drugs that induce the enzyme CYP3A4, such as carbamazepine (Tegretol), may decrease the effects of ziprasidone. Drugs that inhibit the enzyme CYP3A4, such as ketoconazole (Nizoral), may increase the effects of ziprasidone.

Ziprasidone i.m. should not be administered to patients already taking oral ziprasidone.

This is not a complete list of all known or potential drug interactions.  To help prevent problems, always make sure your pharmacist and all prescribers know all the medications you are taking.  This includes over-the-counter drugs and any dietary or herbal supplements or medications.

Common Dosages:  For the treatment of schizophrenia, the recommended initial dose of oral ziprasidone is 20 mg twice a day, with food. In some patients, the dosage may be increased to 80 mg twice a day. It is not necessary to modify the dose for elderly patients. For i.m. administration, the recommended dose is 10 to 20 mg as required. Doses of 10 mg may be given every two hours; doses of 20 mg may be given every four hours up to a maximum of 40 mg/day.

For the treatment of bipolar mania, oral ziprasidone should be initiated at 40 mg twice a day, with food. The second day of treatment, the dose should be increased to 60 mg or 80 mg twice a day and then adjusted based on tolerability and efficacy (suggested range, 40-80 mg twice a day).

Identification: Ziprasidone is available in 20-mg, 40-mg, 60-mg and 80-mg capsules. The capsules are color coded and imprinted in black ink with "Pfizer" and q unique number. The 20-mg capsule is blue and white and imprinted "396." The 40-mg capsule is blue and imprinted "397." The 60-mg capsule is white and imprinted "398." The 80-mg capsule is blue and white and imprinted "399." Injectable ziprasidone is available in a single dose vial of 20 mg/ml (when reconstituted according to label instructions.

Storage: Store this medication at normal room temperature (59° F to 86° F) in a tightly closed, light- and moisture-resistant container.  If you have difficulty opening child-resistant containers, your pharmacist can provide a container that is easier to open.  Keep the medication out of direct sunlight and avoid storing it in a warm or humid area - such as the bathroom or kitchen - to prevent deterioration.  To prevent accidental poisoning, keep all medications out of the reach of children.  Do not take an expired medication.  Do not transfer medication from one container to another.  Carefully discard discontinued medication where children cannot find it.

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Note: These guidelines are for general information only. For more specific information, consult your physician or pharmacist.