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Medication Information:
Amphetamine mixed salts, extended release amphetamine mixed salts
(Generic) - Adderall, Adderall XR (Brand)
Classification: Psycho-stimulant
Common Usage: Adderall is indicated for the treatment of
attention-deficit/hyperactivity disorder (ADHD) in adults and in children ages
three and older it is also indicated for narcolepsy.
Extended-release Adderall
(XR) is indicated for treatment of ADHD only in adults and in children ages six
and older.
For ADHD, these
medications should be prescribed as part of a multimodal treatment plan with
close physician supervision.
Major Side Effects:
The most common side effects in patients using these medications are anorexia
(loss of appetite) and insomnia. Other possible side effects include nausea,
dizziness, heart palpitations, headache, changes in blood pressure or pulse and
rash. Administration of Adderall or Adderall XR may exacerbate symptoms of
behavior disturbances and though disorder in psychotic patients. As with other
psychostimulants indicated for ADHD, there is a potential for precipitating
motor or vocal tics in Tourette's disorder.
These medications should
be taken with caution in people who have a history of drug dependence or
alcoholism. Abuse of Adderall or Adderall XR may lead to tolerance and
dependence. If the drug is withdrawn suddenly after prolonged high-dosage
administration, extreme fatigue or depression may occur.
This is not a complete
list of all known or potential adverse effects. Notify your prescriber or
pharmacist of any symptoms that have started since you began taking this
medication, changing its dose, or adding or changing other medication or diet.
Take care when performing any task (for example, driving or operating machinery)
that requires your attention until you have experience with this drug and are
confident you can perform the task safely.
Interactions with Other Medications: Acidifying agents such as ascorbic
acid (Vitamin C) and fruit juices may lower the absorption of these medications.
Conversely, agents that are alkalinizing such as sodium bicarbonate (Alka
Seltzer) increase absorption.
Adderall/Adderall XR may
increase the activity of tricyclic or other antidepressants, particularly the
tricyclic desipramine (Norpramin) and the monoamine oxidase inhibitor (MAOI)
antidepressants. Use of these medications during or within 14 days of MAOI
antidepressant is contraindicated. Adderall/Adderall XR may counteract the
sedating effects of antihistamines, and may antagonize the hypotensive effects
of blood pressure drugs.
The drug chlorpromazine (Thorazine)
inhibits the central stimulant effects of these medications. Other drugs that
may affect the actions, absorption or side effects of Adderall/Adderall XR
include haloperidol (Haldol), lithium (Eskalith and others) and phenytoin (Dilantin).
This is not a complete
list of all known or potential drug interactions. To help prevent
problems, always make sure your pharmacist and all prescribers know
all the medications you are taking. This includes over-the-counter drugs
and any dietary or herbal supplements or medications.
Common
Dosages: ADHD: in adults, Adderall XR should be started at 10
mg/day (taken in the morning) and increased on a weekly basis by 5-10 mg/day to
maximum dose of 30 mg/day.
For children, Adderall and
Adderall XR should be started in small doses and may be increased gradually in
weekly increments. The dose should be adjusted individually and the lowest
effective dose should be administered.
The usual starting dose of
Adderall (regular/immediate release) for children ages 3-5 years old is 2.5 mg
daily with increases of 2.5 mg on a weekly basis until the desired effect is
achieved. In children 6-years old or older, the recommended starting dose is 5
mg one or twice daily with increases of 5 mg on a weekly basis until the desired
effect is achieved. The first dose should be given in the morning, with
additional doses (1 or 2) administered at intervals of four to six hours. Daily
dosage above 40 mg is not generally recommended.
The recommended starting
dose of Adderall XR in children six years or older is 10 mg/day given in a
single dose in the morning. The dose can be increased at weekly intervals by 5
mg or 10 mg; usually the maximum daily dose does not exceed 30 mg; Afternoon
doses should be avoided due to the potential for insomnia.
Adderall XR capsules
should be taken whole, or the capsule opened and the entire contents sprinkled
on a small amount of apple sauce. The dose of a single capsule should not be
divided.
Narcolepsy: The
usual dose of Adderall (regular/immediate release) is 5 to 60 mg/day in divided
doses taken every 4-6 hours, depending on the patient's response. In adults, the
suggested starting dose is 10 mg/day, taken in the morning. The dose may be
raised by 10 mg on a weekly basis to a maximum of 60 mg/day.
In patients aged 6 to 12
years, the suggested starting dose is 5 mg daily. The dose may be raised by 5 mg
on a weekly basis until optimal response is achieved. In patients 12 years or
older, the suggested starting dose is 10 mg daily. The dose may be raised by 10
mg on a weekly basis until optimal response is achieved.
Identification: ADDERALL: All Adderall tablets are double-scored and
imprinted with "AD" on one side and their mg amount on the other. The 5-mg
tablets are round and blue; 7.5 mg tablets are oval and blue; 10-mg tablets are
round and blue; 12.5-mg tablets are round and orange; 15-mg tablets are oval and
orange; 20-mg tablets are round and orange; 30-mg tablets are round and orange.
ADDERALL XR: All capsules
are imprinted with "Adderall XR" and their mg amount. The 5-mg capsules are
clear/blue; 10-mg capsules are blue/blue; 15-mg capsules are blue/white; 20-mg
capsules are orange/orange; 25-mg capsules are orange/white; 30-mg capsules are
natural/orange.
Storage: Store this medication at normal room temperature (59° F to 86°
F) in a tightly closed, light- and moisture-resistant container. If you
have difficulty opening child-resistant containers, your pharmacist can provide
a container that is easier to open. Keep the medication out of direct
sunlight and avoid storing it in a warm or humid area - such as the bathroom or
kitchen - to prevent deterioration. To prevent accidental poisoning, keep
all medications out of the reach of children. Do not take an expired
medication. Do not transfer medication from one container to another.
Carefully discard discontinued medication where children cannot find it.
This product is a
Schedule II controlled substance.
A
SERVICE OF
. Manisses Communications Group, Inc.
Note: These guidelines are for general information only.
For more specific information, consult your physician or
pharmacist.
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